SAMHD1 抗体
Quick Overview for SAMHD1 抗体 (ABIN2731369)
抗原
See all SAMHD1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Homo sapiens SAM domain and HD domain 1 (SAMHD1)
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Full length human recombinant protein of human SAMHD1 (NP_056289) produced in HEK293T cell.
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亚型
- IgG2b
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应用备注
- WB 1:2000, IF 1:100, FLOW 1:100
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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: "Inhibition of hepatitis B virus replication by a dNTPase-dependent function of the host restriction factor SAMHD1." in: Virology, Vol. 495, pp. 71-8, (2016) (PubMed).
: "SAMHD1 degradation enhances active suppression of dendritic cell maturation by HIV-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 9, pp. 4431-7, (2015) (PubMed).
: "Annexin A3 promotes tumorigenesis and resistance to chemotherapy in hepatocellular carcinoma." in: Molecular carcinogenesis, Vol. 54, Issue 8, pp. 598-607, (2015) (PubMed).
: "SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells." in: PLoS ONE, Vol. 9, Issue 2, pp. e89558, (2014) (PubMed).
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: "Inhibition of hepatitis B virus replication by a dNTPase-dependent function of the host restriction factor SAMHD1." in: Virology, Vol. 495, pp. 71-8, (2016) (PubMed).
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- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
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别名
- SAMHD1
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背景
- This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. COMPLETENESS: complete on the 3' end.
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分子量
- 72 kDa
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基因ID
- 25939
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NCBI登录号
- NM_015474
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HGNC
- 25939
抗原
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